Krivoy Rog

Vaccination: data on side effects from the Covishield vaccine and an agreement with Pfizer

It is noted that 99% of reports of side effects were not serious. In 94% of cases, adverse events were predictable, ie corresponded to the information in the instructions.


Most often, the vaccinated complained of general disorders and disorders at the injection site (66,8%):

temperature rise; fatigue; general weakness;
fever; chills; flu-like condition; redness and pain;
consolidation; swelling of the hand; infiltration; numbness at the injection site. 


Disorders of the musculoskeletal system (11,8%) and neuralgic disorders (11,7%) are quite common: headache; drowsiness or insomnia; tremor of the upper extremities; paresthesias; dizziness; loss of orientation; loss of consciousness.


Most often, patients aged 31-45 years complain of side effects. They are more common in women (approximately 68%).



It will be recalled that the European Medical Agency has concluded that a link is possible between the AstraZeneca vaccine and cases of blood clots.


The report of the EMA Safety Committee stressed that this effect should be included in the list of very rare side effects of the drug. 

The majority of reported cases of thrombosis are among women under 60 years of age. However, based on the available data, specific risk factors have not been confirmed, ie this does not mean that the drug can be dangerous for young women or cause such side effects. 


Blood clots were found in the veins of the brain and peritoneum (thrombosis of the internal veins), in the arteries - with low platelet counts, in some places - with bleeding. 


In total, the EU and the UK have received about 25 million vaccinations with this drug, and among them are known about 62 cases of thrombosis in the brain and 24 cases of internal vein thrombosis. 18 cases were fatal. 

The agency advises to see a doctor immediately if you have the following symptoms after the vaccine: shortness of breath; chest pain; swelling in the leg;
prolonged abdominal pain; neurological symptoms; headache and impaired vision; tiny spots of blood under the skin outside the injection site.



The EMA stressed that Vaxzevria (renamed AStraZeneca) effectively prevents covid and reduces the risk of hospitalization and death.


Recently, Ukraine signed an agreement with the American pharmaceutical corporation Pfizer for the supply of 10 million doses of the vaccine against COVID-19. This was reported in the President's Office.


Later, the head of the Ministry of Health Maxim Stepanov said that all vaccines should arrive within 2021, and the first batches promise to bring in a few months. The Ministry of Health stated that they had signed a framework agreement with Pfizer.


But the head of the State Enterprise "Medical Procurement", which procures drugs, Arsen Zhumadilov questioned the realism of Ukraine's agreement with Pfizer.


According to him, the concept of a framework agreement means preliminary agreements, only the intention to negotiate. The official says that no vaccine in the world has been purchased under such an agreement.


He also drew attention to the fact that the state budget of Ukraine did not contain such financial allocations as 5 billion hryvnias for the purchase of the vaccine. That's about 10 million Pfizer vaccines.



We will remind, vaccination from Covid-19 proceeds in Ukraine since February 24. 500 doses of Covishield, manufactured in India under license from AstraZeneca, and 215 doses of Chinese CoronaVac, which are not yet used, were brought to the country.

As we wrote, in Dnipropetrovsk region more than 29 thousand inhabitants of Dnipropetrovsk region have already signed up for vaccination.


Sources: UNIAN, with the BBC, Photo on a preview from the Internet.


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